Indian News: December 1978

https://digitalcommons.humboldt.edu/tri_county/1003/thumbnail.jp

The co-ordinative practices of temporary organisations

Purpose: This paper aims to explore the necessary mechanisms for coordination in complex industrial networks which are temporary in nature, known as temporary organisations (TOs). Design/methodology/approach: The paper is based on two in-depth case studies conducted in the UK construction industry. Findings: The paper outlines the necessary mechanisms for coordination in TOs – referred to as “scaffolding practices” – which ensure consistency(stability in terms of thinking and action), consensus (agreement) and co-constitutiveness (personal pledges and commitments). Research limitations/implications: The study provides practical implications for situations where actors create temporary organisational specific logics. This “logic” helps explain how actors are able to undertake tasks of finite duration where members lack familiarity and have competing loyalties. Originality/value: The paper is novel in that it represents the first extant attempt to examine “temporary industrial organizations” where individuals from different (often competing) organisations collaborate on a task for a defined period and suggests how coordination may be achieved

Exploring critical media health literacy (CMHL) in the online classroom.

Critical media health literacy (CMHL) is concerned with identifying healthrelated messages in the media, acknowledging the potential effects on health behaviours, critically analyzing the content of the message, and the subsequent application of the message to one’s health behaviours (Levin-Zamir & Bertschi, 2018). This exploratory research examined the CMHL skills of students (n = 120) in an entry-level, online asynchronous health and wellness course, by examining their ability to think critically about health-related themes presented in news media articles online and apply course-based knowledge during a Twitter event. Employing a content analysis of tweets from the event, students were found to illustrate CMHL skills when interacting with peers on Twitter, more than when directly assessing online news media. The findings suggest that the course curriculum be altered to include CMHL skills, to better equip students with the ability to identify accurate health information in the media

New directions for service research: refreshing the process of theorizing to increase contribution

Purpose – For service research to develop as an applied social science there is the need to refresh the process of theorizing so it focuses not only on increasing new academic knowledge but also on knowledge that is managerially relevant. Guidelines are provided to achieve this.Design/methodology/approach – A theorizing process that integrates general theoretic perspectives and contextual research to develop midrange theory is developed. The process is based on the philosophical foundations of pragmatism and abductive reasoning, which has their origins in the 1950s when the management sciences were being established.Findings –A recent research stream that develops midrange theory about customer and actor engagement is used to illustrate the theorizing process.Practical Implications – Practicing managers, customers and other stakeholders in a service system use theory, so there is a need to focus on how theory is used in specific service contexts and how this research leads to academic knowledge that is managerially relevant. Thus, as applied social science, service research needs to explicitly focus on bridging the theory-praxis gap with midrange theory byincorporating a general theoretic perspective and contextual research.Originality/value - The contribution comes from providing a broader framework to guide the theorizing process that integrates general theoretic perspectives and applied research to develop midrange theory. While general theories operate at the most abstract level of conceptualization midrange theories are context-specific, and applied theory (theories-in-use) embedded in empirical researc

Inhibition of \u3cem\u3eRhizobium etli\u3c/em\u3e Polysaccharide Mutants by \u3cem\u3ePhaseolus vulgaris\u3c/em\u3e Root Compounds

Crude bean root extracts of Phaseolus vulgaris were tested for inhibition of the growth of several polysaccharide mutants of Rhizobium etli biovar phaseoli CE3. Mutants deficient only in exopolysaccharide and some mutants deficient only in the O-antigen of the lipopolysaccharide were no more sensitive than the wild-type strain to the extracts, whereas mutants defective in both lipopolysaccharide and exopolysaccharide were much more sensitive. The inhibitory activity was found at much higher levels in roots and nodules than in stems or leaves. Inoculation with either wild-type or polysaccharide-deficient R. etli did not appear to affect the level of activity. Sequential extractions of the crude root material with petroleum ether, ethyl acetate, methanol, and water partitioned inhibitory activity into each solvent except methanol. The major inhibitors in the petroleum ether and ethyl acetate extracts were purified by C18 high-performance liquid chromatography. These compounds all migrated very similarly in both liquid and thin-layer chromatography but were distinguished by their mass spectra. Absorbance spectra and fluorescence properties suggested that they were coumestans, one of which had the mass spectrum and nuclear magnetic resonances of coumestrol. These results are discussed with regard to the hypothesis that one role of rhizobial polysaccharides is to protect against plant toxins encountered during nodule development

Identification of the Plasticity-Relevant Fucose-α(1−2)-Galactose Proteome from the Mouse Olfactory Bulb

Fucose-α(1−2)-galactose [Fucα(1−2)Gal] sugars have been implicated in the molecular mechanisms that underlie neuronal development, learning, and memory. However, an understanding of their precise roles has been hampered by a lack of information regarding Fucα(1−2)Gal glycoproteins. Here, we report the first proteomic studies of this plasticity-relevant epitope. We identify five classes of putative Fucα(1−2)Gal glycoproteins: cell adhesion molecules, ion channels and solute carriers/transporters, ATP-binding proteins, synaptic vesicle-associated proteins, and mitochondrial proteins. In addition, we show that Fucα(1−2)Gal glycoproteins are enriched in the developing mouse olfactory bulb (OB) and exhibit a distinct spatiotemporal expression that is consistent with the presence of a “glycocode” to help direct olfactory sensory neuron (OSN) axonal pathfinding. We find that expression of Fucα(1−2)Gal sugars in the OB is regulated by the α(1−2)fucosyltransferase FUT1. FUT1-deficient mice exhibit developmental defects, including fewer and smaller glomeruli and a thinner olfactory nerve layer, suggesting that fucosylation contributes to OB development. Our findings significantly expand the number of Fucα(1−2)Gal glycoproteins and provide new insights into the molecular mechanisms by which fucosyl sugars contribute to neuronal processes

Indian News: October 1978

https://digitalcommons.humboldt.edu/tri_county/1002/thumbnail.jp

Photoactivatable Glycopolymers for the Proteome-Wide Identification of Fucose-α(1-2)-Galactose Binding Proteins

Although fucose-α(1-2)-galactose (Fucα(1-2)Gal)-containing glycans have been implicated in cognitive processes such as learning and memory, their precise molecular mechanisms are poorly understood. Here we employed the use of multivalent glycopolymers to enable the first proteome-wide identification of weak affinity, low abundance Fucα(1-2)Gal glycan-binding proteins (GBPs). Biotin-terminated glycopolymers containing photoactivatable cross-linking groups were designed to capture and enrich GBPs from rat brain lysates. Candidate proteins were tested for their ability to bind Fucα(1-2)Gal, and the functional significance of the interaction was investigated for the synaptic vesicle protein SV2a using a knockout mouse system. The results suggest a role for SV2a-Fucα(1-2)Gal interactions in SV2a trafficking and synaptic vesicle recycling. More broadly, our studies outline a general chemical approach for the systems-level discovery of novel GBPs

The role of shared intentions in the emergence of service ecosystems

With the increased prevalence of ecosystems across sectors, understanding what conditions enable their formation is important for both researchers and managers. Service-dominant logic (S-D logic) focuses on service ecosystems, in which actors are interdependent, and characterizes them as layered and nested within three levels (micro, meso, and macro). To understand their formation, this study draws from work in philosophy and the social sciences to introduce the concept of shared intentionality, an aspect of collective agency whose specific conditions result from and foster interdependence among actors, and to acknowledge the mediating role of the meso level in emergence. With these concepts, this study addresses a research question on how service ecosystems are formed and what role individual and collective agency play in this process. This study contributes to S-D logic research by offering a new understanding of service ecosystem formation as a process of emergence in which the development of shared intentions enables collective agency. To synthesize the contribution, this study uses a case to illustrate a conceptual framework in which the sharing of intentions among interdependent actors drives service ecosystem emergence step-by-step across distinct dynamic levels